Box86 and Wine are both tools for running x86 applications on ARM-based Linux systems, but they work differently.
Box86 is a compatibility layer that converts x86 and x86_64 Linux binaries to ARM and AARCH64. Box86 and Box64 work similarly to Apple's Rosetta, which does not fully emulate x86 and x86_64 Linux binaries, but uses native libraries where possible, which makes it far more performant than QEMU and enables many modern commercial games Can run on Linux.
Wine, on the other hand, is a compatibility layer that enables running Windows applications on Linux systems. Rather than a virtual machine or emulator that emulates Windows' internal logic, Wine converts Windows API calls into POSIX calls on the fly, eliminating the performance and memory penalties of other methods and allowing you to neatly integrate Windows applications into your desktop.
In some cases, you may need to use Box86 and Wine together. For example, if you want to run a Windows x86 application on an ARM Linux system, you can use Box86 to convert the x86 binaries to ARM, and then use Wine to run the application.
As for your question, is it necessary to use 64-bit Wine with 64-bit Debian, the answer is not necessarily. 64-bit Wine will only run on 64-bit installations and requires 32-bit libraries to be installed to run 32-bit Windows applications. However, you can install 32-bit Wine on a 64-bit Debian system to run 32-bit Windows applications. This may be simpler since no additional installation of 32-bit libraries is required. However, please note that this may cause some 64-bit Windows applications to not run. |